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Definitions of lovastatin

  1. an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate Scrapingweb Dictionary DB
  2. A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver. Medical Dictionary DB
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